Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties
Particularly, for this polymorphism the frequency of the MTRR 66G allele ranges from 35.8 to 54.3% among Caucasians, from 40.0 to 48.0% in mixed Brazilian populations, and from 41.5 to 62.5% in Asians (Wang et al., 2008
It may only cause issues if it is taken in excess or if you have some existing medical conditions
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